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While regulating the long non-coding RNA/miRNA pathway offers high specificity, the systemic delivery of RNA-modulating drugs poses challenges, such as the risk of off-target effects, obstacles in clinical scalability, and challenges in targeting efficacy (117)

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The European Medicines Agency (EMA) and MHRA continuously monitor the safety profile of all licensed medications through pharmacovigilance systems

The primary outcome measured was the diagnosis of new breast cancer during the study period